The conundrum of watchful waiting versus pre-emptive surgery in asymptomatic aortic stenosis: are we any closer to an answer?

نویسندگان

  • Milind Y Desai
  • Amgad Mentias
چکیده

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Quality-of-life implications of immediate surgery and watchful waiting in asymptomatic aortic stenosis: a decision-analytic model.

BACKGROUND- Traditional management of severe aortic stenosis (AS) is based on delay in aortic valve replacement (AVR) until the development of symptoms. Surgery for asymptomatic AS has been proposed to reduce the small risk of sudden death before AVR and avoid heart failure (HF) after AVR. Because a trial to compare these options is unlikely, we developed a Markov model to inform the choice bet...

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Predicting outcome in patients with asymptomatic aortic stenosis.

Although the annual risk of cardiovascular mortality has been well described for individuals with symptomatic aortic stenosis, the morbidity and mortality for those with asymptomatic severe aortic stenosis is not as well known. Currently the American Heart Association/American College of Cardiology recommends a “watchful waiting” strategy for those with asymptomatic aortic stenosis.1 This invol...

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Exercise hemodynamics and risk assessment in asymptomatic aortic stenosis.

More than half a century ago, in the American Journal of Cardiology, Dr Paul Wood aptly described aortic stenosis (AS) as “a simple mechanical fault which, if severe enough, imposes a heavy burden on the left ventricle and sooner or later overcomes it.”1 Our subsequent understanding of the pathophysiology of AS, using more sophisticated tools than those at Dr Wood’s disposal, has confirmed his ...

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[Comment on "Initial surgical versus conservative strategies in patients with asymptomatic severe aortic stenosis"].

BACKGROUND Current guidelines generally recommend watchful waiting until symptoms emerge for aortic valve replacement (AVR) in asymptomatic patients with severe aortic stenosis (AS). OBJECTIVES The study sought to compare the long-term outcomes of initial AVR versus conservative strategies following the diagnosis of asymptomatic severe AS. METHODS We used data from a large multicenter regis...

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عنوان ژورنال:
  • Polskie Archiwum Medycyny Wewnetrznej

دوره 126 9  شماره 

صفحات  -

تاریخ انتشار 2016